The 10 Best Weight Loss Pills and Diet Supplements That Work Today

Weight-Loss Supplement

Diet pills market is getting saturated each day.

Every year a number of weight loss pills are made by the different manufacturer, and each of them has claimed their product as the most effective one.

It is also to ensure that some of the weight loss supplement products ended up getting people scammed.

This is the most frustrating phase where some people get suspicious about the efficacy of diet pills.

Most of the diet pills extracted from the natural source and made up of the herbal ingredients are found to be most effective.

This buyer guide will help you choose the best dietary supplements for yourself.

Risking your health over cheaper weight loss treatment can harm you in many ways, so before buying any diet pills, do read it to clarify your options further.

Table of Contents

10 Best Weight Loss Pills on the Market

Some of the best weight loss supplements are included to let you chose the best option for the effective weight loss you have been looking for.

1. PhenQ

PhenQ is one of the most powerful sources for weight loss.

PhenQ had gained maximum fame in a short period of time when it successfully helped about 190 thousand of its customers achieving their weight loss goals.

The ingredients of PhenQ are safe and natural, which helps you burn the calories faster than you expected.

PhenQ is effective in burning the rigid fat that your body has been contained for a long period of time.

The directions for the use of PhenQ is very simple; one pill with breakfast and one with lunch should be taken.

The product contains a high amount of caffeine, that is why it is not recommended to take it after 3 p.m. or consume any beverages includes a high amount of caffeine.

How Does It Work?

PhenQ efficiently blocks the fat production and help you eat less because of its appetite suppressant formula.

By the help of caffeine, it will enhance the process of thermogenic fat burning, even amid the process, your mind will be highly sharp and focused.

Thermogenic effect (heat production) is enhanced, which burns the calories more effectively.

Active Ingredients in PhenQ

Capsimax powder: Increases thermogenic effects

Caffeine: Works as a CNS Stimulant, keeps your mind altered and focused throughout the day. Inhibits muscle fatigue and helps in losing weight.

Nopal: Flushes out extra fluid from your body. As a rich source of amino acid, it will keep your body energized and makes your muscles harder since fluid retention becomes low.

Chromium picolinate : Inhibits the sugar or carbs cravings, which are the main reason for weight gain. Also, maintains the sugar level.

Weight Loss Claims and Published Studies

Some of the clinical researches have been conducted on the effects of PhenQ.

While comparing its effects with the controlled group on Placebo, it was concluded that about 3.44% of overall body weight was reduced.

The rate of total body fat reduction is 7.4% leaving muscle mass increased its size by 3.8%.

The effects of PhenQ ingredients are truly remarkable as they have brought positive changes in about 90% of their consumers.

Risks and Side Effects

According to some medical leading websites, consumption of high amounts of caffeine can lead to reversible insomnia and increased heart rate.

In the case of PhenQ, a higher dose can bring those effects for an indefinite period.

Apart from this, PhenQ is highly contraindicated in pregnant women or those who are under 18 years.

Some minor, adverse reactions include nausea, gastric problem and mild vertigo.

2. HCG Weight Loss Supplement

This diet supplement comes from the family of weight loss dietary supplement, which doesn’t require any prescription.

It has various product lines which merge different varieties of ingredients.

Some of the brands of hCG diet drops include real human chorionic gonadotropin hormone while the other uses natural ingredients to mimic the potency of the hormone.

One of its manufacturers, Biosource Labs, states that they put raw ingredients through extensive quality assurance procedures.

How Does It Work?

Amongst every ingredient of this supplement, hCG hormone is the ingredients that are mainly linked to fat loss.

The appetite suppressing and thermogenic properties of the hormone make it easy for other ingredients to share a synergistic reason, which is to further accelerate the fat loss phenomenon.

Several drops should be taken before every meal of the day (8 drops per day), which can further be increased to 10 drops before each meal.

More than 10 drops of intake per day are highly not recommended. Each bottle contains about 107mg of caffeine, which in combination is similar to have 6 cups of coffee a day.

Claims and Published Studies

Short and precise researches available at the webpage of several hCG weight loss providers which reportedly dropped 10.9 lbs in 50 overweight individuals.

The trial is basically about the consumption of human chorionic gonadotropin for 30 days, which is the ingredient for most of the weight loss drops.

The product itself doesn’t provide us with any clinical research undergone on it, but another study suggests the effects of this hormone in a group of subjects.

The combination of the hormone and other vitamins, especially the B vitamin, can elevate the rate of metabolism in our body by 11%, which speeds up the fat burning process up to 29%.

Risks and Side Effects

People who are sensitive to this hormone or this form of diet might experience some adverse effects like sleeplessness, nervousness, tachycardia, muscle tremors.

3. Garcinia Cambogia

The fruit is found in the Asian and African tropical regions. Most of the population started trying this natural weight loss treatment after it gets featured by Dr Oz, a very admirable personality, and a diet scientist.

For a potential weight loss, the active ingredient of HCA (Hydroxycitric Acid) in Garcinia Cambonia extract is very much beneficial.

Garcinia supplement is mainly available in capsule form.

How Does It Work?

The active constituent in this dietary supplement acts as an inhibitor in fat conversion.

Usually, nutrients like carbohydrates convert into fat by getting deposited in cells, which in the case of Garcinia Cambogia intake is blocked.

In some cases, it has shown a potential appetite suppressing property.

The daily dose is 500 mg capsule taken 30 minutes before each meal.

Claims and Published Studies

In the Journal of Obesity, there was a review published about men and women who undertook Garcinia Cambogia.

They lost about 2 pounds than the group of people who didn’t take it.

The reduction of appetite could be the hallmark of this review. In many studies, the weight loss effect of this fruit was illustrated very well in rats, but no evidence of human clinical trials was found.

Risks and Side Effects

It was conducted in the study on mice that Garcinia dietary supplement caused testicular toxicity on high dosages.

Whereas, in human, there were no side effects reported unless it’s dragged to the maximum dose.

4. Phen375

Phen375 is a premium nutraceutical and thermogenic fat burner designed to target an effective weight loss.

For some people, it worked just great in terms of burning the extra fat from the body.

The dietary supplement is a safe and legal choice for healthy weight management. Compared to many other fat burners, Phen375 works way faster.

Phen375 improves the metabolism of your body and controls the appetite intensity, which makes you lose fat faster.

With an economical price, Phen375 doesn’t require any prescription as well.

Take 2 tablets daily, one pill after breakfast and lunch.

How Does It Work?

Give a start to thermogenesis, which fastens up the metabolism to burn more calories than intake.

It takes control over the junk and carbs craving as a result of which your body gets the least amount of calories.

Phen375 mimics a hormone which stops extra fat bulging to the cellular level.

Active Ingredients

Dimethypentylamine Hydrochloride: Improves metabolic state

Capsaicin: Thermogenic agent. Helps in blood circulation, diminishes the chances of fat bulging in the arteries.

Trimethylxanthine: Appetite suppressant. Transform calories into energy instead of storing it in the form of fats.

L-Carnitine-Amino acid that keeps the fats away from the vital organs.

Natural Caffeine Powder: CNS Stimulant

Sympathomimetic Amine: Improves your physical/workout skills

Claims and Published Studies

The maker of Phen375 claims fast and effective weight loss.

It has the capability to diminish the growth of fats dwelling subcutaneously and those which located deep down.

Phen375 has reportedly shredded 15 lbs of weight in 2 weeks.

Risks and Side Effects

Some of the possible side effects which you might experience after using Phen375 are:

  • Inconsistency in passing stool, dizziness, nervousness.
  • It contains caffeine and other sources for CNS Stimulant, which might lead to insomnia and increased heart rate if consumed in high dose.

5. Conjugated Linoleic Acid (CLA)

Conjugated linoleic acid (CLA), as it is generally termed, is ideal for the improvement of immunity levels and has proven to be scientifically effective in treating overweight and obesity.  

Many other dietary supplements are available in the market, but CLA is of one of the most effective ones as it is safe, and there are no side effects.  CLA possesses insulin resistance and aids in the improvement of metabolic activity.

How Does It Work?

Conjugated Linoleic Acid aids in the improvement of metabolism levels and produces energy to perform daily bodily functions. It is also helpful in the effective functioning of the cell membranes and gives more strength.  Also, it helps in muscle repair and improvement of muscles.  

The essential elements present in CLA helps in entering the cells of the body instead of just getting stored as fats.  CLA also has enough sensitivity to insulin, and it has shown excellent results if taken in the right dosage.

One needs to give thought to CLA dosage so that it does not go overboard and you should be careful of the amount of dosage you take every time. Find a doctor or family physician to consult with before you take the dosage.

CLA also has antioxidant properties and helps in building lean muscles.  Moreover, it has proven to reduce the harmful effects of cardio diseases and ailments if the right dosage is followed.

Claims and Published Studies

Linoleic acid (LA) is a polyunsaturated fatty acid (omega-6). It is in the form of liquid at room temperature and has no color. It is coded as n-6 in physiology and a carboxylic acid with an 18-carbon chain. 

Linoleic can be traced in some vegetable oils. You can find it in oils like sunflower, safflower and corn oil.

Linoleic acid is one of the most important fatty acids. Essential fat acids fall under the group that will supply the necessary nutritional elements to mammals. If your body falls short of omega-6 fatty acid, you can notice the loss of hair and dry hair. If you are injured, it will take a long time to be healed from the wound. 

The conjugated fatty acid can be derived from animal tissues and plants. There are two types of conjugated fatty acids. One type of fatty acids have conjugated double bonds, and the other type of fatty acids are separated by methylene groups (two or more). Ruminant animals, meat and dairy products are great sources for conjugated systems. 

There is growing concern about the medicinal value CLA, especially for a cancer treatment. The anti-atherosclerosis will improve your immune system. It will also remove the bad cholesterol and thus, you will be free from heart ailments. It will promote the accumulation of proteins and burns excess fat in the body. The product is offered as a nutritional supplement in the market.

Risks and Side Effects

One of the side-effects that users defined as a positive sign is feeling full sooner because of which they eat less and feel lighter.

Other secondary effect includes mild stomach cramp.

6. Lipozene

This product is an upgraded version of Glucomannan. The extracts are obtained from an Asian plant that has been used by the people as a healthy weight loss remedy for centuries.

Changing the name doesn’t lead any change in ingredients, though but the packaging is changed to an attractive bottle.

The capsules of Lipozene should be taken twice (one after each meal) with a glass of water most preferably.

How Does It Work?

Lipozene capsule contains Glucomannan which is actually a water-soluble fiber, sometimes also known as Konjac.

The gelatinous material within the capsule expands in the stomach after engulfing, thus increasing the sensation of having a full stomach with no appetite sensation.

By this way, you can count this non prescription weight loss treatment as an appetite suppressant.

The capsule literally turns into a gel after pouring it in a glass of water.

The water-soluble fiber of Lipozene doesn’t get absorbed through the gut but is excreted in an unchanged form.

Like most of the laxatives, it takes away the toxins and free fats remaining in the stomach.

Claims and Published Studies

It is because of the water-soluble fiber Glucomannan, which gives Lipozene credit for weight loss.

About 14 weight loss studies have been done on its effects, which show an impressive improvement in LDL cholesterol, triglycerides, even total cholesterol and overall body weight.

When combined with a healthy diet, Lipozene can help to lose 8-10 pounds in 5 weeks.

Risks and Side Effects

Lipozene capsule must be consumed with a full glass of water to prevent the blockage in the throat.

Some of the adverse reactions which users experience are nausea, abdominal pain, bloating, gas and diarrhea.

7. Plexus Slim

With the advancement in medical science, weight loss supplements are available in various dosage forms.

Pills and capsules have become old, and now there are products available in a solution form.

Plexus Slim is a health drink that has formulated a powerful microbiome activating formula that is precisely effective in achieving a weight loss goal.

With each drink, you will be provided with a dose of gut-friendly microbes that are clinically proven to improve your gut health and encourages weight loss.

With a maximum dose of beneficial prebiotic, your glucose level will be maintained, and the fastened metabolism will aid you lose weight in a short period of time.

The flavored drinks are very pleasing to the taste buds, and the user will not be tired of its taste since the availability is in various flavors.

How Does It Work?

At first, the formula was made for the diabetic patient to bring their glucose level to a normal range.

Later, some ingredients have been added to the formula which has a marked effect on weight loss, such as green coffee bean extract, Garcinia Cambogia extract, chromium etc.

When you take a single drink of Plexus Slim, it increases Lactobacillus by 365 times and Bifidobacterium by 290 times, which contributes to many health issues.

Akkermansia microbes a metabolism enhancing bacteria is drastically increased in a single dose which speeds up your body process to utilize fats into energy.

It cuts down the glucose, which is beneficial in weight loss.

Active Ingredients

Garcinia Cambogia fruit extract- Controls appetite and prevents the stored fats from bulging around the belly and other extremities.

Chromium- Aids to athletic performance. Control blood sugar in both type 1 and type 2 diabetes. Reduce bad cholesterol and battles with depression.

Green coffee bean- Burns fat faster while exercising, also a powerful antioxidant, which normalizes the blood sugar ratio.

Alpha Lipoic Acid- Prevents cell damage within the body, breaks down the carbs and supplies energy to other organs. Also a very rich source of Vitamin E and C.

Natural Flavors- To mask the taste

Claims and Published Studies

When assesing the safety of a dietary supplement like Plexus Slim, it is crucial to know whether the ingredients it has undergone any testing or research.

In accordance with the Journal of the American Medical Association, Garcinia Cambogia has failed to prove any results of weight loss in a given sample observed with Placebo.

Green coffee bean extracts, on the other hand, has got the attention of the journal Gastroenterology Research and Practice which says that results from trials of Green Coffee Beans Extract were promising though, but the study itself was conducted on poor methodological quality.

Lipoic acid, when taken 1800 mg per day, can provide a weight loss effect, but that what is not included in the Plexus Slim drink.

Risks and Side Effects

After taking a look almost of thousands of reviews, we have gathered some of the common undesirable effects of Plexus Slim includes nausea, constipation, abdominal pain, high blood pressure, tachycardia and shaky gestures.

8. Forskolin

From an ancient Ayurveda medicine, Forskolin was introduced as a fat burners.

It is basically obtained from Coleus Forskohlii which is a tropical plant.

Forskolin should be taken one or two per day before 30 minutes of a meal. Usually, it is advised to take it with a glass of water.

How Does It Work?

Forskolin performs a weight management tactic on a cellular level.

Cyclic adenosine monophosphate is a nucleotide used in the RNA, and Forskolin enhances the level of this nucleotide which has a principal function to eliminate the stored fat from the fat cells.

In this way, the maximum amount of energy is provided to your body, and it also provides a synergistic effect on other fat burning agents.

Claims and Published Studies

In a study conducted, it was estimated that the rate at which Forskolin decreases body fat percentage is significant as compared to the placebo group.

The increase in testosterone caused by Forskolin tends to increase bone mass as well, especially in men.

It also improves the growth of lean muscle mass.

Risks and Side Effects

Sometimes with an increased level of Testosterone, men grow more hair than usual.

Forskolin also lowers your blood pressure, which then leads to drowsiness, fatigue and other symptoms associated with low blood pressure.

9. Raspberry Ketones

Raspberry ketone is a chemical entity that is found mainly in raspberries and some other fruits like peaches, grapes, vegetables and maple.

The Raspberry Ketones have been in practice for a weight loss.

The fame began to rise when Dr Oz demonstrated its effects on a national TV show.

They even named it a “Miracle fat burner in a bottle” for the year 2012.

The effects of Raspberry Ketones have been demonstrated in mice, where it resulted in a potential weight loss.

However, any data for human trial hasn’t been submitted.

Some population uses Raspberry Ketones for hair loss and as a skin revitalizing agent.

It has an identical fragrance, which is why it is also being used in cosmetics and food items where scenting is necessary.

How Does It Work?

The pills can be taken in a quantity of 2 tablets per day. You can have it with or without food.

The dose of 100 mg to 1400 mg recommended each day.

This Raspberry fruit is believed to speed up the metabolism and also interfere with a hormone called Adiponectin, which accelerates the process of fat burning.

Adiponectin can also reduce your hunger, but the conclusive scientific evidence is still missing if it really promotes weight loss.

Claims and Published Studies

Some of the effects of Raspberry fruit extract are true, such as the increased amount of energy, boost up the metabolism and control your curb cravings.

However, it would be asinine to call this a perfect choice for weight loss.

The maker of Raspberry supplements claims that it induces an effective weight loss.

This is because of the study conducted on rats where Raspberry Ketone was found remarkably effective in weight management. It would require a higher dose in human and such dose hasn’t been determined.

Risks and Side Effects

During pregnancy or lactation, cautions must be taken. Some side-effects include lowering of blood sugar level.

10. Leptigen

Leptigen is a diet pill that works as a metabolism boosting and appetite suppressing agent.

The generic has some brand names amongst which Meratrim is to highlight.

The manufacturer claims its ingredients to be clinically proven and safe for the use.

The formula says that it could help in achieving weight loss, boost metabolism and control the blood sugar level.

How Does It Work?

The hormone Leptin secretes from the fat cells and is responsible for the hunger induction. Leptigen impact the level of leptin, which diminishes the curb cravings.

The metabolism boosting phenomenon will further double fat burning effects. A single dose of Leptin is one pill.

For an effective weight loss take 2 doses per day before 30 minutes of breakfast and lunch.

Active Ingredients

Decaffeinated green tea extract: A natural fat burner, the caffeine has been removed from the formula so you won’t get any impaired kidney reactions.

Chromium poly nicotinate: A rich source of vitamin, in a study where the effects of Chromium compared with the Placebo, it helped dieters to lose weight fast.

MeraTrim: Composed of two active compounds, Sphaeranthus indicus & Garcinia mangostana. About these compounds, two studies have revealed that they work for weight loss. Also, it works when you take MeraTrim 800 mg per day.

Caffeine: Enhances fat burning, also keep the mind active and focused.

Claims and Published Studies

One of the main Leptin’s ingredients (MeraTrim) was subjected to a clinical study published in Obesity and Journal of Medicinal Food, showed the efficacy of MeraTrim in weight loss.

The other ingredient of Leptigen (Chromium) is clinically proven to improve blood sugar and cholesterol level.

Risks and Side Effects

In situations like pregnancy, lactation or before a surgical procedure, Leptigen is not allowed for intake.

Do not take it before bedtime because of the high content of caffeine.

How Weight-Loss Pills Actually Work?

Numerous of studies has been conducted on weight loss or diet pills. Researchers suggest there are 3 mechanisms by which diet pills actually work.

These are as under.

1. By Boosting Up The Metabolism

Boosting up metabolism simply means that the rate of your body organs to execute any function will be enhanced.

Similarly, it will burn the most amount of calories, which ultimately results in weight loss.

A number of calories your body burns will be higher than the amount you take in.

Appetite suppressants act side by side with the metabolism boosters, thereby providing each other with the synergistic effect.

A metabolism booster does have effects on physical and mental activities, but for a short time being.

One of the most excellent examples of this category is caffeine, usually, after an intake of coffee your mind and body get elated, and you perform any tasks efficiently as soon as its effects are present in your blood.

Caffeine in coffee helps you burn fat because of its metabolism booting property.

2. By Suppressing Appetite

This is the most common effect of overall diet pills.

Reduction of appetite is a primary factor that effectively targets your weight gain issue.

When the intake of calories becomes less on a daily basis, it will lead to maximum fat loss.

Some class of weight loss drugs supplements worked as appetite suppressants have been erased from the market because they increased the risk of death after which natural replacements are more preferred.

Reducing appetite is the most common practice for losing weight.

3. By Blocking The Absorption

A compound such as fats are broken down in our body and get absorbed.

Absorption blockers inhibit the breakdown of fat because of which it does not get absorbed into the body.

No fat absorption means no weight gain. While elements which do not affect weight passes easily through.

These are the three common mechanisms which weight loss pill wields on us.