The 10 Best Weight Loss Pills and Diet Supplements That Work Today

Weight-Loss Supplement

Diet pills market is getting saturated each day.

Every year a number of weight loss pills are made by the different manufacturer, and each of them has claimed their product as the most effective one.

It is also to ensure that some of the weight loss supplement products ended up getting people scammed.

This is the most frustrating phase where some people get suspicious about the efficacy of diet pills.

Most of the diet pills extracted from the natural source and made up of the herbal ingredients are found to be most effective.

This buyer guide will help you choose the best dietary supplements for yourself.

Risking your health over cheaper weight loss treatment can harm you in many ways, so before buying any diet pills, do read it to clarify your options further.

10 Best Weight Loss Pills on the Market

Some of the best weight loss supplements are included to let you chose the best option for the effective weight loss you have been looking for.

1. PhenQ

PhenQPhenQ is one of the most powerful supplements for weight loss.

PhenQ had gained maximum fame in a short period of time when it successfully helped about 190 thousand of its customers achieving their weight loss goals.

The ingredients of PhenQ are safe and natural, which helps you burn the calories faster than you expected.

This non prescription weight loss pill is effective in burning the rigid fatty acid that your body has been contained for a long period of time.

How Does It Work?

PhenQ efficiently blocks the fat production and help you eat less because of its appetite suppressant formula.

By the help of caffeine, it will enhance the process of thermogenic fat burning, even amid the process, your mind will be highly sharp and focused.

Thermogenic effect (heat production) is enhanced, which burns the calories more effectively.

While comparing its effects with the controlled group on Placebo, it was concluded that about 3.44% of overall body mass index was reduced.

The rate of total body fat reduction is 7.4% leaving muscle mass increased its size by 3.8%.

Active Ingredients in PhenQ

Capsimax powder: Increases thermogenic effects

Caffeine: Works as a CNS Stimulant, keeps your mind altered and focused throughout the day. Inhibits muscle fatigue and helps in losing weight.

Nopal: Flushes out extra fluid from your body. As a rich source of amino acid, it will keep you feeling energized and makes your muscles harder since fluid retention becomes low.

Chromium picolinate : Inhibits the sugar or carbs cravings, which are the main reason for body weight gain. Also, maintains the sugar level.

Risks and Side Effects

According to some medical leading websites, consumption of high amounts of caffeine can lead to reversible insomnia and increased heart rate.

In the case of PhenQ, a higher dose can bring those effects for an indefinite period.

Apart from this, PhenQ is highly contraindicated in pregnant women or those who are under 18 years.

Some minor, adverse reactions include nausea, gastric problem and mild vertigo.

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2. Weight Loss Drops

Diet dropletsThis low-fat diet supplement comes from the family of weight loss dietary supplement, which doesn’t require any prescription.

It has various product lines which merge different varieties of ingredients.

Some of the brands of hCG diet include real human chorionic gonadotropin hormone while others use amino acids and natural ingredients to mimic the potency of the hormone.

How Does It Work?

Amongst every ingredient of this supplement, hCG hormone is the ingredients that are mainly linked to fat loss.

The appetite suppressing and thermogenic properties of the hormone make it easy for other ingredients to share a synergistic reason, which is to further accelerate the fat loss phenomenon.

Short and precise researches available at the webpage of several hCG weight loss providers which reportedly dropped 10.9 lbs in 50 overweight individuals.

The trial is basically about the consumption of human chorionic gonadotropin for 30 days, which is the ingredient for most of the weight loss drops.

The product itself doesn’t provide us with any clinical research undergone on it, but another study suggests the effects of this hormone in a group of subjects.

The combination of the hormone and other vitamins, especially the B vitamin, can elevate the rate of metabolism in our body by 11%, which speeds up the fat burning process up to 29%.

Risks and Side-Effects

People who are sensitive to this hormone or this form of diet might experience some adverse effects like sleeplessness, nervousness, tachycardia, muscle tremors.

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3. Garcinia Cambogia

Garcinia Extract BottleThe fruit is found in the Asian and African tropical regions.

Most of the population started trying this natural weight loss treatment after it gets featured by Dr Oz, a very admirable personality, and a diet scientist.

For a potential weight loss, the active ingredient of HCA (Hydroxycitric Acid) in Garcinia Cambonia extract is very much beneficial.

Garcinia supplement is mainly available in capsule form.

How Does It Work?

The active constituent in this dietary supplement acts as an inhibitor in fat conversion.

Usually, nutrients like carbohydrates convert into fat by getting deposited in cells, which in the case of Garcinia Cambogia intake is blocked.

In some cases, it has shown a potential appetite suppressing property.

In the Journal of Obesity, there was a review published about men and women who undertook Garcinia Cambogia (1).

They lost about 2 pounds than the group of people who didn’t take it.

The reduction of appetite could be the hallmark of this review. In many clinical trials, the weight loss effect of this fruit was illustrated very well in rats, but no evidence of human clinical trials was found.

Risks and Side-Effects

It was conducted in the study on mice that Garcinia dietary supplement caused testicular toxicity on high dosages.

Whereas, in human, there were no side effects reported unless it’s dragged to the maximum dose.

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4. Phen24

Phen24Phen24 is a premium nutraceutical and thermogenic fat burner designed to target an effective weight loss.

For some people, it worked just great in terms of burning the extra fat from the body.

The dietary supplement is a safe and legal choice for healthy weight management since their facility has been approved by the Food and Drug Administration (FDA). Compared to many other fat burners, Phen24 works way faster.

Phen24 improves the metabolism of your body and controls the appetite intensity, which makes you lose and burn fat faster.

With an economical price, Phen24 doesn’t require any prescription as well.

How Does It Work?

Give a start to thermogenesis, which fastens up the metabolism to burn more calories than intake.

It takes control over the junk and carbs craving as a result of which your body gets the least amount of calories.

Phen24 mimics a hormone which stops extra fat bulging to the cellular level.

It has the capability to diminish the growth of fats dwelling subcutaneously and those which located deep down.

Active Ingredients

Glucomannan: Absorbs water and reduces cravings

Chromium Picolinate : Thermogenic agent. Helps in blood circulation, diminishes the chances of fat bulging in the arteries.

Phenylalanine: Appetite suppressant. Transform calories into energy instead of storing it in the form of fats.

Choline Bitartrate: Keeps the fats away from the vital organs.

Green tea extract: One of the most effective fat burning agents

Risks and Side-Effects

  • Inconsistency in passing stool, dizziness, nervousness.
  • It contains caffeine and other sources for CNS Stimulant, which might lead to insomnia and increased heart rate if consumed in high dose.

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5. Lean Optimizer

Lean Optimizer

Lean Optimizer is produced by 4HFL, owned by Dr. Sam Robbins and a reputable brand which manufactures health products since 1998.

The generic has some brand names amongst which Meratrim is to highlight.

The formula confirms that it could help to lose fat, boost metabolism and control the blood sugar level.

How Does It Work?

One of the main Leptin’s ingredients (MeraTrim) was subjected to a clinical study published in Journal of the American Academy of Nutrition and Dietetics (3), showed the efficacy of MeraTrim in weight loss.

The hormone Leptin secretes from the fat cells and is responsible for the hunger induction. Leptigen impact the level of leptin, which diminishes the curb cravings.

The metabolism boosting phenomenon will further double fat burning effects. A single dose of Leptin is one pill.

Active Ingredients

Decaffeinated green tea extract : A natural fat burner, the caffeine such as in a green coffee bean extract has been removed from the formula so that you won’t get any impaired kidney reactions.

Chromium poly nicotinate: A rich source of nutrition, in a study where the effects of Chromium compared with the Placebo, it helped dieters to lose weight fast.

MeraTrim: Composed of two active compounds, Sphaeranthus indicus & Garcinia mangostana. About these compounds, two studies have revealed that they work for weight loss. Also, it works when you take MeraTrim 800 mg per day.

Risks and Side-Effects

In situations like pregnancy, lactation or before a surgical procedure, Lean Optimizer is not allowed for intake.

Do not take it before bedtime because of the high content of caffeine.

Order Lean Optimizer here

6. Meratol

Meratol pillThis product is an upgraded version of Nopal.

The extracts are obtained from a Mexican plant that has been used by the people as part of a healthy eating and fat loss remedy for centuries.

Changing the name doesn’t lead any change in ingredients, though but the packaging is changed to an attractive bottle.

The capsules of Meratol should be taken once (two in the morning) with a glass of water most preferably.

How Does It Work?

Meratol capsule contains Cactinea Powder which is actually a water-soluble fiber, sometimes also known as Cacti-Nea.

The gelatinous material within the capsule expands in the stomach after engulfing, thus increasing the sensation of having a full stomach with no appetite sensation.

By this way, you can count this non prescription weight loss treatment as an appetite suppressant.

The capsule literally turns into a gel after pouring it in a glass of water.

The water-soluble fiber of Meratol doesn’t get absorbed through the gut but is excreted in an unchanged form.

Like most of the laxatives, it takes away the toxins and free fats remaining in the stomach.

Risks and Side-Effects

Some of the adverse reactions which users experience are nausea, abdominal pain, bloating, gas and diarrhea.

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7. Phen375

Natural Phentermine 375Phen375 is another natural phentermine and is part of the thermogenic family, which is designed to burn fat by increasing the speed of your bodies metabolism.

In addition, it has excellent appetite suppression capabilities – which means it works on two different levels in an aim to improve the number of calories you burn, and to lessen the intensity of hunger you feel throughout the day.

Phen375 has also been found to lower your total cholesterol levels.

This can be very useful for basic health reasons, and will go a long way towards defending your heart from debilitating disease and other conditions which can reduce your cardiovascular fitness.

How Does It Work?

At first, the formula was made for the overweight people to bring their metabolism level to a normal range.

Later, some ingredients have been added to the formula which has a marked effect on weight loss, such as Caffeine Powder Anhydrous, Coleus Forskolii Root, Cayenne Pepper, etc.

When you take a single drink of Phen375, it increases metabolic rate by 20% and decreases appetite, which is beneficial to lose weight.

Active Ingredients

Caffeine Powder Anhydrous: Controls appetite and prevents the stored fats from bulging around the belly and other extremities.

L-Carnitine: Aids to athletic performance. Control blood sugar in both type 1 and type 2 diabetes. Reduce bad cholesterol and battles with depression.

Cayenne Pepper (Capsicum): Burns fat faster while on a diet and exercise, also a powerful antioxidant, which normalizes the blood sugar ratio.

Risks and Side Effects

After taking a look almost of thousands of reviews, we have gathered some of the common undesirable effects of Phen375 includes nausea, constipation, abdominal pain, high blood pressure, tachycardia and shaky gestures.

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8. Forskolin

Pure Forskolin 250From an ancient Ayurveda medicine, Forskolin was introduced as a fat burners.

It is basically obtained from Coleus Forskohlii which is a tropical plant.

Forskolin should be taken one or two per day before 30 minutes of a meal.

Usually, it is advised to take it with a glass of water.

How Does It Work?

In a study conducted, it was estimated that the rate at which Forskolin decreases body fat percentage is significant as compared to the placebo group (2).

Forskolin performs a weight management tactic on a cellular level.

Cyclic adenosine monophosphate is a nucleotide used in the RNA, and Forskolin enhances the level of this nucleotide which has a principal function to eliminate the stored fat from the fat cells.

In this way, the maximum amount of energy is provided to your body, and it also provides a synergistic effect on other fat burning agents.

The increase in testosterone caused by Forskolin tends to increase bone mass as well, especially in men.

It also improves the growth of lean muscle mass.

Risks and Side Effects

Sometimes with an increased level of Testosterone, men grow more hair than usual.

Forskolin also lowers your blood pressure, which then leads to drowsiness, fatigue and other symptoms associated with low blood pressure.

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9. Raspberry Ketones

Raspberry-ketone BottleRaspberry ketone is a chemical entity that is found mainly in raspberries and some other fruits like peaches, grapes, vegetables and maple.

The Raspberry Ketones have been in practice for a weight loss.

The fame began to rise when Dr Oz demonstrated its effects on a national TV show.

The effects of Raspberry Ketones have been demonstrated in mice, where it resulted in a potential weight loss.

However, any data for human trial hasn’t been submitted.

How Does It Work?

This Raspberry fruit is believed to speed up the metabolism and also interfere with a hormone called Adiponectin, which accelerates the process of fat burning.

Adiponectin can also reduce your hunger, but the conclusive scientific evidence is still missing if it really promotes weight loss.

However, it would be asinine to call this a perfect choice for weight loss.

This is because of the study conducted on rats where Raspberry Ketone was found remarkably effective in weight management. It would require a higher dose in human and such dose hasn’t been determined.

Risks and Side-Effects

During pregnancy or lactation, cautions must be taken. Some side effects include lowering of blood sugar level.

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10. Conjugated Linoleic Acid (CLA)

CLA BottleConjugated linoleic acid (CLA), as it is generally termed, is ideal for the improvement of immunity levels and has proven to be scientifically effective in treating overweight and obesity.

CLA will promote the accumulation of proteins and burns excess fat in the body.

The product is offered as a nutritional supplement in the market.

Many other dietary supplements are available in the market, but CLA is of one of the most effective ones as it is safe, and there are no side effects.

CLA possesses insulin resistance and aids in the improvement of metabolic activity.

How Does It Work?

Conjugated Linoleic Acid aids in the improvement of metabolism levels and produces energy to perform daily bodily functions. It is also helpful in the effective functioning of the cell membranes and gives more strength.

The essential elements present in CLA helps in entering the cells of the body instead of just getting stored as fats.  CLA also has enough sensitivity to insulin, and it has shown excellent results if taken in the right dosage.

There is growing concern about the medicinal value CLA, especially for a cancer treatment. The anti-atherosclerosis will improve your immune system. It will also remove the bad cholesterol and thus, you will be free from heart ailments.

One needs to give thought to CLA dosage so that it does not go overboard and you should be careful of the amount of dosage you take every time. Find a doctor or family physician and get the medical advice before you take the dosage, especially if you are currently taking prescription medications.

CLA also has antioxidant properties and helps in building lean muscles.  Moreover, it has proven to reduce the harmful effects of heart disease and ailments if the right dosage is followed.

Risks and Side Effects

One of the side-effects that users defined as a positive sign is feeling full sooner because of which they eat less and feel lighter.

Other secondary effect includes mild stomach cramp.

Before taking any weight-loss drugs, pills, or supplements, make sure you consult with a doctor beforehand. A complementary of proper diet and exercise may be necessary when consuming specific products.


  1. Igho Onakpoya, Rachel Perry, Shao Kang Hung, Edzard Ernst, Barbara Wider (2011). The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. Obesity. 509038. doi: 10.1155/2011/509038
  2. Michael P. Godard  Brad A. Johnson  Scott R. Richmond (2012). Body Composition and Hormonal Adaptations Associated with Forskolin Consumption in Overweight and Obese Men. Obesity Research Journal, Volume 13, Issue 8:1301-1484. doi: 10.1038/oby.2005.162
  3. Z.M. Saiyed, Francis C Lau, James P. Lugo, A.T. Mishra (2012). Efficacy and Tolerability of Meratrim for Weight Management. Journal of the American Academy of Nutrition and Dietetics 112(9):A43. doi: 10.1016/j.jand.2012.06.150
Jerry Connel is a fully qualified nutritionist and personal trainer. He is also currently undertaking a Ph.D. in Food Science at Oregon State University in the US. He has been a keen bodybuilder throughout his adulthood and is well-versed with health supplements.